About
Sassafras Southern Bistro is a southern American restaurant in Greenville, South Carolina that serves up classic southern cuisine with its own unique and modern twist. Using locally-sourced, fresh ingredients, Sassafras creates flavorful and thoughtfully crafted dishes that capture the flavors and traditions of the American south. With attentive and friendly service, Sassafras Southern Bistro is a perfect dining spot for any occasion.
Restaurant Features
Facilities & Amenities
Restroom
Bar- Wifi Available
Kid High Chair
Alcohol
Happy Hour
Wheelchair Access
Parking
- Paid Parking Lot
Accepted Payments
- Credit Card
- Apple Pay
- Google Pay
Must Try Dishes
Sassafras Southern Bistro in Greenville, South Carolina offers an array of delightful dishes that are simply irresistible. Indulge in their famous Shrimp and Grits, where perfectly cooked shrimp nestle atop a bed of creamy, stone-ground grits, creating a harmonious blend of flavors. For a taste of Southern comfort, the Fried Chicken and Waffles is a must-try, with crispy, golden-brown chicken accompanied by fluffy waffles and a drizzle of sweet maple syrup. Seafood lovers will relish the Lowcountry Boil, an enticing medley of plump shrimp, tender crab, and juicy sausage, all steeped in a mouthwatering blend of spices. Finally, don't miss the Fried Green Tomatoes, tangy and crisp, served with creamy remoulade sauce, which is a perfect blend of textures and flavors. Sassafras Southern Bistro promises an unforgettable culinary experience that captures the essence of Southern cuisine.
Ratings for Sassafras Southern Bistro
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Reviews for Sassafras Southern Bistro
We only show the 3 most relevant reviews to save you time.
A truly delectable dining experience. From the hostess, to the waiter, to the management checking on us, we were extremely well taken care of from start to finish. And dinner? Well, out of this world delicious. Will be back for sure! Dine in: Yes Outdoor seating: Yes Takeout: Yes Curbside pickup: No … More
Southern charm and good food at its finest!! Spectacular meal in a beautifully decorated old building. The crab cakes and steak were fantastic! Andrew our sever was fantastic, a true professional. The owner even came buy to say hello. I would highly recommend this place.
Perfect southern food. Pimento cheese, fried pickles, blackened seafood, grits, collards - come here for your southern fix! Great deal on inventive cocktails including mule Monday's. Definitely check it out if you're in town!
Photos

Business Hours
| Sunday: | Closed |
| Monday: | 5:00 PM - 9:00 PM |
| Tuesday: | 5:00 PM - 9:00 PM |
| Wednesday: | 5:00 PM - 9:00 PM |
| Thursday: | 5:00 PM - 9:00 PM |
| Friday: | 5:00 PM - 9:30 PM |
| Saturday: | 4:30 PM - 9:30 PM |
